Dextro-transposition of the great arteries causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Cafer Zorkun, M.D., Ph.D. [3]; Keri Shafer, M.D. [4]; Assistant Editor(s)-In-Chief: Kristin Feeney, B.S. [5]

Overview

The causes of most congenital heart defects are unknown.

Causes

The cause of most congenital heart defects is unknown. Factors in the mother that may increase the risk of this condition include:

Age over 40
Alcoholism
Diabetes
Prenatal nutrition
Rubella or other viral illness during pregnancy
Generally, TGA is not known to be associated with any specific single gene defect, but some studies have shown possible genetic association in some cases of TGA, involving deletions of chromosome 22q11.

References

Overview