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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Diabetic nephropathy causes

Introduction

Overview

Overview

Diabetes mellitus both type1 and type 2 is the major cause. It is thought to be due to hyperfiltration through the renal glomeruli. The chances of developing diabetic nephropathy is markedly increased in patients with a diabetic sibling or parent who has diabetic nephropathy. these observations have been seen in both type 1 and type 2 diabetes. The genetic basis underlying the heritability of diabetic nephropathy is not known.

Causes

Causes

  • Diabetes, type 1 or 2
  • Persistent, uncontrolled hyperglycemia
  • Hypertension in the presence of diabetes.
  • Diabetes with smoking
  • High blood cholesterol and diabetes
  • Genetic factors
References[1]

References[1]

  1. ↑ Chang MS, Hsu YH (July 2018). “The role of IL-20 in chronic kidney disease and diabetic nephropathy: Pathogenic and therapeutic implications”. J. Leukoc. Biol. doi:10.1002/JLB.MR1217-489R. PMID 29999545.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]