Diabetic nephropathy causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]

Overview

Diabetes mellitus both type1 and type 2 is the major cause. It is thought to be due to hyperfiltration through the renal glomeruli. The chances of developing diabetic nephropathy is markedly increased in patients with a diabetic sibling or parent who has diabetic nephropathy. these observations have been seen in both type 1 and type 2 diabetes. The genetic basis underlying the heritability of diabetic nephropathy is not known.

Causes

Diabetes, type 1 or 2
Persistent, uncontrolled hyperglycemia
Hypertension in the presence of diabetes.
Diabetes with smoking
High blood cholesterol and diabetes
Genetic factors

References[1]

References^[1]

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↑ Chang MS, Hsu YH (July 2018). “The role of IL-20 in chronic kidney disease and diabetic nephropathy: Pathogenic and therapeutic implications”. J. Leukoc. Biol. doi:10.1002/JLB.MR1217-489R. PMID 29999545.

[pmid29999545-1] Chang MS, Hsu YH (July 2018). “The role of IL-20 in chronic kidney disease and diabetic nephropathy: Pathogenic and therapeutic implications”. J. Leukoc. Biol. doi:10.1002/JLB.MR1217-489R. PMID 29999545.

[1]

Diabetic nephropathy causes

Overview

Causes

References[1]

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References^[1]