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Diabetic neuropathy overview

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Overview

Diabetic neuropathies are neuropathic disorders that are associated with diabetes mellitus. These conditions are thought to result from diabetic microvascular injury involving small blood vessels that supply nerves (vasa nervorum). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy; mononeuropathy; mononeuropathy multiplex; diabetic amyotrophy; a painful polyneuropathy; autonomic neuropathy; and thoracoabdominal neuropathy.

Historical Perspective

Historical Perspective

Classification

Classification

Diabetic neuropathy can be classified into two main types:

  • Sensorimotor
  • Autonomic

[1]

Pathophysiology

Pathophysiology

Causes

Causes

Differentiating Diabetic neuropathy other Diseases

Differentiating Diabetic neuropathy other Diseases

Epidemiology and Demographics

Epidemiology and Demographics

Risk Factors

Risk Factors

Screening

Screening

Natural History, Complications and Prognosis

Natural History, Complications and Prognosis

Diagnosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Treatment

Surgery

Medical Therapy

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case Studies

Case #1

References

References

  1. Deli G, Bosnyak E, Pusch G, Komoly S, Feher G (2013). “Diabetic neuropathies: diagnosis and management”. Neuroendocrinology. 98 (4): 267–80. doi:10.1159/000358728. PMID 24458095.

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