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Dienestrol

Introduction

Overview

Overview

Dienestrol is a synthetic estrogen.

Synthesis

Synthesis

Dienestrol synthesis:[1]
  1. Pinacol coupling of p–acetoxy–propiophenone.
  2. Dehydration of the thus-obtained glycol with a mixture of acetyl chloride and acetic anhydride leads to the transoid diene system (bis–β-Methylstyrene-type).
  3. Saponification removes the acetate groups and thus affords dienestrol.
See also

See also

References

References

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]