Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Diethylthiambutene
Introduction
Diethylthiambutene (Thiambutene, Themalon, Diethibutin, N,N-Diethyl-1-methyl-3,3-di-2-thienylallylamine) is an opioid analgesic drug developed in the 1950s [1] which was mainly used as an anesthetic in veterinary medicine.[2][3] It is now under international control under Schedule I of the UN Single Convention On Narcotic Drugs 1961, presumably due to high abuse potential, although little more information is available.
References
- ↑ BECKETT AH, CASY AF, HARPER NJ, PHILLIPS PM. Analgesics and their antagonists: some steric and chemical considerations. II. The influence of the basic group on physico-chemical properties and the activity of methadone and thiambutene-type compounds. Journal of Pharmacy and Pharmacology. 1956 Nov;8(11):860-73.
- ↑ Hayes MJ. The use of thiambutene hydrochloride. The Veterinary Record. 1968 Nov 16;83(20):528.
- ↑ Harbison WD, Slocombe RF, Watts SJ, Stewart GA. Thiambutene and acepromazine as analgesic and preanaesthetic agents in horses and sheep. Australian Veterinary Journal. 1974 Dec;50(12):543-6.