Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Differentiating drug-induced lupus erythematosus from other diseases
Introduction
Overview
Overview
Differentiating Drug-Induced Lupus Erythematosus from other Diseases
Differentiating Drug-Induced Lupus Erythematosus from other Diseases
As a reminder, rheumatologic conditions tend to declare themselves over time, as opposed to immediately displaying all the classic clinical manifestations of the disease.
There is an inherited difficulty in distinguishing true drug-induced autoimmunity from an exacerbation of pre-existing autoimmunity or unmasking of a second autoimmune disease. It will become even more important to recognize medication-induced lupus syndromes given the expanding list of medications associated with DIL.
Here are possible differentials to DIL:
- Idiopathic systemic lupus erythematosus
- Systemic sclerosis (scleroderma)
- Rheumatoid arthritis
- Connective tissue diseases
- Granulomatosis with polyangiitis
- Fibromyalgia
- Lichen planus
- Chronic radiation dermatitis
- Rosacea
- Psoriasis
- Dermatomyositis
- Granuloma annulare
- Actinic keratosis
https://www.visualdx.com/visualdx/diagnosis/drug-induced+lupus+erythematosus?diagnosisId=51883&moduleId=101 https://www.thepermanentejournal.org/issues/43-the-permanente-journal/original-research-and-contributions/7458-drug-induced-lupus,-a-one-time-hit-or-a-harbinger-of-future-autoimmunity-a-case-report.html
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]