Diffuse esophageal spasm natural history, complications and prognosis

If left untreated, most patients remain asymptomatic over the course of time. Very few cases report progression to Achalasia and nut cracker esophagus.

• DES is generally non-progressive, if left untreated there are very few case reports of progression to Achalasia and nut cracker esophagus.

• Common complications of DES include:
  • Achalasia
  • Nut cracker esophagus

• Prognosis is generally excellent and the disease has no mortality recorded.