Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Diffuse large B cell lymphoma history and symptoms
Introduction
Overview
Overview
The most common symptoms of diffuse large B cell lymphoma include a rapidly enlarging, non-painful mass that may be located in neck, groin, or abdomen. The less common symptoms of diffuse large B cell lymphoma include fever, weight loss, and drenching night sweats also known as ”B symptoms”[1][2].
Common Symptoms
Common Symptoms
- Mass/Lump
- Rapidly enlarging lump (enlarged lymph nodes)
- Painless
- May be present in neck, groin or abdomen
- It is not uncommon to have lymphoma outside the Lymph nodes(Extranodal sites) and can lead to the rapid Progression to Large lumps.
- Localized symptoms:
Other symptoms might depend on the organ of Involvement for example DLBCL in Chest can lead to shortness of breath or cough while DLBCL involving gut or Stomach can cause Abdominal Pain/ Diarrhea/ Bleeding etc.
Constitutional/B Symptoms
Constitutional/B Symptoms
- Fever
- Unexplained Weight loss( more than 10 percent over a period of 6 Months)
- Night sweats
References
References
- ↑ Swerdlow SH, et al (editors). WHO classification of tumours of haematopoietic and lymphoid tissues. 4th edition. 2008. International Agency for Research on Cancer (IARC), Lyon, Franc
- ↑ Tilly H, et al. Diffuse large B-cell lymphoma (DLBCL): ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Annals of Oncology. 2015; 26: v116-v125
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2] Anila Hussain, MD [3]