Diffuse panbronchiolitis history and symptoms

DPB can be characterized by a number of symptoms and histological features (those detected by analysis of tissues).

If left untreated, as DPB progresses, signs of bronchiectasis begin to present themselves. These symptoms include chronic shortness of breath, severe cough, pooling of sputum, thickening of bronchiolar walls, hypoxemia, and dilation (enlargement) of the bronchiolar passages.^[1][2] This eventually becomes life-threatening, leading to respiratory failure.^[1]