
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Distributive shock
Introduction
Overview
Overview
Distributive shock is, as in hypovolemic shock, caused by an insufficient intravascular volume of blood. This form of relative hypovolemia is the result of blood vessel dilation.
Classification
Classification
Examples of this form of shock are:
- Septic shock – This is caused by an overwhelming infection leading to vasodilation, such as by Gram negative bacteria i.e. Escherichia coli which releases an endotoxin which produces adverse biochemical, immunological and occasionally neural mechanisms which are harmful to the body. It is treated by antibiotics, fluid replacement, and vasoconstrictors.
- Anaphylactic shock – Caused by a severe anaphylactic reaction to an allergen, antigen, drug or foreign protein causing the release of histamine which causes widespread vasodilation. Leading to hypotension and increase capillary permeability.
- Acute adrenal insufficiency: Acute adrenal insufficiency is not infrequently the result of discontinuing corticosteroid treatment without tapering the dosage.
- Neurogenic shock– Neurogenic shock is the rarest form of shock. It is caused by trauma to the spinal cord resulting in the sudden loss of autonomic and motor reflexes below the injury level. Without stimulation by sympathetic nervous system the vessel walls relax uncontrolled, resulting in a sudden decrease in peripheral vascular resistance, leading to vasodilation and hypotension.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
