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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Drotaverine

Introduction

Drotaverine (INN, also known as drotaverin) is an antispasmodic drug, structurally related to papaverine. Drotaverine is a selective inhibitor of phosphodiesterase 4, and has no anticholinergic effects.

A small 2003 study found drotaverine to be nearly 80% effective in treating renal colic.[1] It has also been used to accelerate labor.[2]

References

  1. ↑ Romics I, Molnár DL, Timberg G; et al. (2003). “The effect of drotaverine hydrochloride in acute colicky pain caused by renal and ureteric stones”. BJU Int. 92 (1): 92–6. doi:10.1046/j.1464-410X.2003.04262.x. PMID 12823389.
  2. ↑ Singh KC, Jain P, Goel N, Saxena A (2004). “Drotaverine hydrochloride for augmentation of labor”. Int J Gynaecol Obstet. 84 (1): 17–22. PMID 14698825.


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