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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Drug-induced lupus erythematosus epidemiology and demographics

Introduction

Overview

Overview

Prevalence

Prevalence

  • In the U.S.: As many as 10% of the approximately 500,000 cases of SLE may be DIL.
  • It is estimated that 6 to 12% of all SLE cases are of drug-induced lupus type. The incidence has been reported to be of 15,000 to 30,000 per year in the U.S..[1]
Case-Fatality Rate

Case-Fatality Rate

  • There is no information about case-fatality rate on drug-induced lupus, but it can be potentially fatal. 16466117 [2]
Age

Age

Patients with DILE tend to be older (50–70 years old) than those with SLE (average age 29 years at diagnosis). Elderly persons generally are more susceptible to DILE.

Gender

Gender

In DIL, no significant statistical difference is apparent in the prevalence for males versus females. In contrast, SLE affects women with considerably higher frequency than men (female-to-male ratio of 9:1).

Ethnicity

Ethnicity

More whites than blacks develop DIL; more blacks than whites present with SLE.

References

References

  1. ↑ “StatPearls”. 2021. PMID 28722919.
  2. ↑ Finks SW, Finks AL, Self TH (2006). “Hydralazine-induced lupus: maintaining vigilance with increased use in patients with heart failure”. South Med J. 99 (1): 18–22. doi:10.1097/01.smj.0000197121.12352.19. PMID 16466117.


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]