Drug-induced lupus erythematosus historical perspective

Hydralazine was the first agent to be associated with the development of lupus-like symptoms in 1954. Since then, more than 100 drugs have been identified as the cause of drug-induced lupus, with the list expanding with the development of newer biologic agents each year. https://www.ncbi.nlm.nih.gov/books/NBK441889/

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