
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions โ written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
EP400
Introduction
E1A-binding protein p400 is a protein that in humans is encoded by the EP400 gene.[1][2][3]
Interactions
Interactions
EP400 has been shown to interact with Transformation/transcription domain-associated protein,[2] RuvB-like 1[2] and Myc.[2]
References
References
- โ Margolis RL, Abraham MR, Gatchell SB, Li SH, Kidwai AS, Breschel TS, Stine OC, Callahan C, McInnis MG, Ross CA (Jul 1997). “cDNAs with long CAG trinucleotide repeats from human brain”. Hum Genet. 100 (1): 114โ22. doi:10.1007/s004390050476. PMIDย 9225980.
- โ 2.0 2.1 2.2 2.3 Fuchs M, Gerber J, Drapkin R, Sif S, Ikura T, Ogryzko V, Lane WS, Nakatani Y, Livingston DM (Aug 2001). “The p400 complex is an essential E1A transformation target”. Cell. 106 (3): 297โ307. doi:10.1016/S0092-8674(01)00450-0. PMIDย 11509179.
- โ “Entrez Gene: EP400 E1A binding protein p400”.
Further reading
Further reading
- Doyon Y, Cรดtรฉ J (2004). “The highly conserved and multifunctional NuA4 HAT complex”. Curr. Opin. Genet. Dev. 14 (2): 147โ54. doi:10.1016/j.gde.2004.02.009. PMIDย 15196461.
- Nagase T, Kikuno R, Ishikawa K, et al. (2000). “Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro”. DNA Res. 7 (2): 143โ50. doi:10.1093/dnares/7.2.143. PMIDย 10819331.
- Nagase T, Nakayama M, Nakajima D, et al. (2001). “Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro”. DNA Res. 8 (2): 85โ95. doi:10.1093/dnares/8.2.85. PMIDย 11347906.
- Nakayama M, Kikuno R, Ohara O (2003). “Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs”. Genome Res. 12 (11): 1773โ84. doi:10.1101/gr.406902. PMCย 187542. PMIDย 12421765.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899โ903. doi:10.1073/pnas.242603899. PMCย 139241. PMIDย 12477932.
- Cai Y, Jin J, Tomomori-Sato C, et al. (2003). “Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex”. J. Biol. Chem. 278 (44): 42733โ6. doi:10.1074/jbc.C300389200. PMIDย 12963728.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). “Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40โ5. doi:10.1038/ng1285. PMIDย 14702039.
- Doyon Y, Selleck W, Lane WS, et al. (2004). “Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans”. Mol. Cell. Biol. 24 (5): 1884โ96. doi:10.1128/MCB.24.5.1884-1896.2004. PMCย 350560. PMIDย 14966270.
- Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). “Large-scale characterization of HeLa cell nuclear phosphoproteins”. Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130โ5. doi:10.1073/pnas.0404720101. PMCย 514446. PMIDย 15302935.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121โ7. doi:10.1101/gr.2596504. PMCย 528928. PMIDย 15489334.
- Chan HM, Narita M, Lowe SW, Livingston DM (2005). “The p400 E1A-associated protein is a novel component of the p53 –> p21 senescence pathway”. Genes Dev. 19 (2): 196โ201. doi:10.1101/gad.1280205. PMCย 545875. PMIDย 15655109.
- Samuelson AV, Narita M, Chan HM, et al. (2005). “p400 is required for E1A to promote apoptosis”. J. Biol. Chem. 280 (23): 21915โ23. doi:10.1074/jbc.M414564200. PMIDย 15741165.
- Tyteca S, Vandromme M, Legube G, et al. (2006). “Tip60 and p400 are both required for UV-induced apoptosis but play antagonistic roles in cell cycle progression”. EMBO J. 25 (8): 1680โ9. doi:10.1038/sj.emboj.7601066. PMCย 1440826. PMIDย 16601686.
