Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
End-stage disease
Introduction
An end-stage disease is when an organ or disease is at its very worst condition. When this happens, the organ is barely functioning. An example would be someone with a heart in an end-stage disease. The organ has been irreversibly and extensively damaged. This results in some very serious and permanent symptoms.