Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Endometrial cancer classification
Introduction
Overview
Overview
Endometrial cancer may be classified according to histology into either type I comprising 80% of endometrial cancers or type II accounting for around 20%.
Classification
Classification
Endometrial cancer may be classified according to histology into 2 types:[1]
| Type | Histology | Prognosis | Pathogenesis | Prevalence |
|---|---|---|---|---|
| Type I | Endometroid (adenocarcinoma) | Favorable (estrogen-responsive) | • May arise from atypical hyperplasia • Linked to unopposed estrogen stimulation |
80% |
| Type II | • Endometroid • Serous • Clear cell • Mucinous • Squamous • Mesonephric • Undifferentiated |
Typically bad prognosis | • Develops from atrophic endometrium • Not linked to hormonally driven pathogenesis |
15-20% |
References
References
- ↑ Bokhman JV (1983). “Two pathogenetic types of endometrial carcinoma”. Gynecol Oncol. 15 (1): 10–7. PMID 6822361.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Roukoz A. Karam, M.D.[2]