Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Endometrial cancer medical therapy
Introduction
Overview
Overview
The optimal therapy for endometrial cancer depends on the stage at diagnosis. A combination of chemotherapy and radiation therapy is indicated in stages IIIB- IV.
Medical Therapy
Medical Therapy
- The optimal therapy for endometrial cancer depends on the stage at diagnosis. A combination of chemotherapy and radiation therapy is indicated in stages IIIB- IV.
- Chemotherapy is not the first-line treatment option for patients with stage I-III endometrial cancer. Surgery is the mainstay of treatment.
- Chemotherapy without prior surgery is usually reserved for patients with stage IV endometrial cancer or patients that are not surgical candidates.
- Typically a platinum based combination regimen or triple druge therapy is used:[1]
- Endocrine therapy is also used with favorable results in patients with:[2]
- Endometroid endmetrial cancer
- Express estrogen and progesterone receptors
- Asymptomatic disease
References
References
- ↑ Fleming GF (2007). “Systemic chemotherapy for uterine carcinoma: metastatic and adjuvant”. J Clin Oncol. 25 (20): 2983–90. doi:10.1200/JCO.2007.10.8431. PMID 17617530.
- ↑ Decruze SB, Green JA (2007). “Hormone therapy in advanced and recurrent endometrial cancer: a systematic review”. Int J Gynecol Cancer. 17 (5): 964–78. doi:10.1111/j.1525-1438.2007.00897.x. PMID 17442022.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Roukoz A. Karam, M.D.[2]