Endothelial lipase

Endothelial lipase is a form of lipase secreted by vascular endothelial cells in tissues with high metabolic rates and vascularization, such as the liver, lung, kidney, and thyroid gland.^[1] Unlike the lipases that hydrolyze triglycerides, endothelial lipase primarily hydrolyzes phospholipids.^[1]

It was first characterized in 1999.^[2]

References

↑ ^1.0 ^1.1 Yu JE, Han SY, Wolfson B, Zhou Q (2018). “The role of endothelial lipase in lipid metabolism, inflammation, and cancer”. Histology and Histopathology. 33 (1): 1–10. doi:10.14670/HH-11-905. PMC 5858721. PMID 28540715.
↑ Jaye M, Lynch KJ, Krawiec J, et al. (1999). “A novel endothelial-derived lipase that modulates HDL metabolism”. Nat. Genet. 21 (4): 424–8. doi:10.1038/7766. PMID 10192396.

External links

endothelial+lipase,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

[pmid28540715-1] 1.0 ^1.1 Yu JE, Han SY, Wolfson B, Zhou Q (2018). “The role of endothelial lipase in lipid metabolism, inflammation, and cancer”. Histology and Histopathology. 33 (1): 1–10. doi:10.14670/HH-11-905. PMC 5858721. PMID 28540715.

[pmid10192396-2] Jaye M, Lynch KJ, Krawiec J, et al. (1999). “A novel endothelial-derived lipase that modulates HDL metabolism”. Nat. Genet. 21 (4): 424–8. doi:10.1038/7766. PMID 10192396.

[1]

[2]

Endothelial lipase

References

External links

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