Endothelin receptor antagonist

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

A endothelin receptor antagonist (ERA) is a drug which blocks endothelin receptors.

Two main kinds of ERAs exist:

• selective ERA (e.g. sitaxsentan), which affect endothelin A.
• dual ERAs,(e.g. bosentan) which affect both endothelin A and B .^[1]