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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Eosinophilia future or investigational therapies

Introduction

  • Eosinophilia is a laboratory finding and is not specifically a target of treatment in most cases
  • If the severely elevated eosinophilia count is felt to be the cause of the patient’s symptoms, there are a number of treatments that specifically lower eosinophil counts
  • Anti-IL5 antibody Mepolizumab is under investigation for use in hypereosinophil syndrome. Mepolizumab has shown potential to rapidly reduce eosinophil counts in trials and reduce the need for corticosteroids. [1]

References

  1. ↑ Rothenberg et al. Treatment of Patients with the Hypereosinophilic Syndrome with Mepolizumab. NEJM 2008; 358:1215-1228