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Eosinophilic esophagitis other diagnostic studies

Introduction

Overview

Overview

Endoscopic abnormalities in patients with EoE include fixed esophageal ring which is corrugated, white exudates or plaques, longitudinal furrows, mucosal pallor, diffuse esophageal narrowing, mucosal fragility leading to esophageal lacerations during the endoscopy.

Other Diagnostic Studies

Other Diagnostic Studies

Endoscopy

Biopsy

  • Characteristic features are as follows:
    • > 20 eosinophils/0.24 mm2.
    • Papillae are elongated
    • Papillae reach into the top 1/3 of the epithelial layer
    • Basal cell hyperplasia; > 3 cells thick or >15% of epithelial thickness
H&E stain of esophagus biopsy showing eosinophilic esophagitis, manifested by an infiltration of eosinophils in the lamina propria
References

References

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ajay Gade MD[2]]