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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Epidural hematoma pathophysiology

Introduction

Overview

Overview

Epidural hematoma is the result of the bleeding within the epidural space, which lies between dura mater and skull bone. The main cause of epidural hematoma is typically head injury that results in a break of the temporal bone and bleeding from the middle meningeal artery in the epidural space. Because the bleeding is caused by arterial rupture, it has a high tendency to progress and it causes a hematoma in epidural space. Progression of bleeding may expand the hematoma and cause increasing of the intracranial pressure and it may lead to brain herniation. Occasionally epidural hematoma may occur as a result of a Bleeding disorders or blood vessel malformation or after CNS surgery or lumbar acupunctures or Spinal injections or metastatic cancer and sometimes is may occur spontaneously.

Pathophysiology

Pathophysiology

Pathogenesis

Associated Conditions

Associated Conditions

Overview

Overview

References

References

  1. ↑ Scheibl A, Calderón EM, Borau MJ, Prieto RM, González PF, Galiana GG (2012). “Epidural hematoma”. J Pediatr Surg. 47 (2): e19–21. doi:10.1016/j.jpedsurg.2011.10.078. PMID 22325415.
  2. ↑ Yu J, Guo Y, Xu B, Xu K (2016). “Clinical importance of the middle meningeal artery: A review of the literature”. Int J Med Sci. 13 (10): 790–799. doi:10.7150/ijms.16489. PMC 5069415. PMID 27766029.
  3. ↑ Yanagawa Y, Sakamoto T, Okada Y (2007). “Clinical features of temporal tip epidural hematomas”. J Neurosurg. 107 (1): 18–20. doi:10.3171/JNS-07/07/0018. PMID 17639868.
  4. ↑ 4.0 4.1 Maugeri R, Anderson DG, Graziano F, Meccio F, Visocchi M, Iacopino DG (2015). “Conservative vs. Surgical Management of Post-Traumatic Epidural Hematoma: A Case and Review of Literature”. Am J Case Rep. 16: 811–7. PMC 4652627. PMID 26567227.
  5. ↑ 5.0 5.1 Mitsuyama T, Ide M, Kawamura H (2004). “Acute epidural hematoma caused by contrecoup head injury–case report”. Neurol Med Chir (Tokyo). 44 (11): 584–6. PMID 15686177.
  6. ↑ Chen H, Guo Y, Chen SW, Wang G, Cao HL, Chen J; et al. (2012). “Progressive epidural hematoma in patients with head trauma: incidence, outcome, and risk factors”. Emerg Med Int. 2012: 134905. doi:10.1155/2012/134905. PMC 3536037. PMID 23320175.
  7. ↑ 7.0 7.1 Morsing IE, Brons P, Th Draaisma JM, van Lindert EJ, Erasmus CE (2009). “Hemophilia a and spinal epidural hematoma in children”. Neuropediatrics. 40 (5): 245–8. doi:10.1055/s-0030-1248247. PMID 20221963.
  8. ↑ 8.0 8.1 Paraskevopoulos D, Magras I, Polyzoidis K (2013). “Spontaneous spinal epidural hematoma secondary to extradural arteriovenous malformation in a child: a case-based update”. Childs Nerv Syst. 29 (11): 1985–91. doi:10.1007/s00381-013-2214-5. PMID 23812629.
  9. ↑ 9.0 9.1 Kim B, Moon SH, Kim SY, Kim HJ, Lee HM (2010). “Delayed Spinal Epidural Hematoma after En Block Spondylectomy for Vertebral Ewing’s Sarcoma”. Asian Spine J. 4 (2): 118–22. doi:10.4184/asj.2010.4.2.118. PMC 2996623. PMID 21165315.
  10. ↑ 10.0 10.1 Chen CY, Liu GC, Sheu RS, Huang CL (1997). “Bacterial meningitis and lumbar epidural hematoma due to lumbar acupunctures: a case report”. Kaohsiung J Med Sci. 13 (5): 328–31. PMID 9226976.
  11. ↑ 11.0 11.1 Simmons NE, Elias WJ, Henson SL, Laws ER (1999). “Small cell lung carcinoma causing epidural hematoma: case report”. Surg Neurol. 51 (1): 56–9. PMID 9952124.
  12. ↑ Babatola BO, Salman YA, Abiola AM, Okezie KO, Oladele AS (2012). “Spontaneous epidural haematoma in sickle cell anaemia: case report and literature review”. J Surg Tech Case Rep. 4 (2): 135–7. doi:10.4103/2006-8808.110271. PMC 3673360. PMID 23741596.
  13. ↑ Yogarajah M, Agu CC, Sivasambu B, Mittler MA (2015). “HbSC Disease and Spontaneous Epidural Hematoma with Kernohan’s Notch Phenomena”. Case Rep Hematol. 2015: 470873. doi:10.1155/2015/470873. PMC 4631867. PMID 26576305.
  14. ↑ Kim HS, Lee SK, Kim SW, Shin H (2011). “Chronic Spinal Epidural Hematoma Related to Kummell’s Disease”. J Korean Neurosurg Soc. 49 (4): 231–3. doi:10.3340/jkns.2011.49.4.231. PMC 3098428. PMID 21607183.
  15. ↑ Fong CY, Hlaing CS, Tay CG, Kadir KA, Goh KJ, Ong LC (2016). “Longitudinal extensive transverse myelitis with cervical epidural haematoma following dengue virus infection”. Eur J Paediatr Neurol. 20 (3): 449–53. doi:10.1016/j.ejpn.2016.01.012. PMID 26900103.
  16. ↑ Rosen DA, Hawkinberry DW, Rosen KR, Gustafson RA, Hogg JP, Broadman LM (2004). “An epidural hematoma in an adolescent patient after cardiac surgery”. Anesth Analg. 98 (4): 966–9, table of contents. PMID 15041581.
  17. ↑ Bang J, Kim JU, Lee YM, Joh J, An EH, Lee JY; et al. (2011). “Spinal epidural hematoma related to an epidural catheter in a cardiac surgery patient -A case report-“. Korean J Anesthesiol. 61 (6): 524–7. doi:10.4097/kjae.2011.61.6.524. PMC 3249578. PMID 22220233.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]