Normoblast
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Overview
An erythroblast is a type of red blood cell which still retains a cell nucleus. It is the immediate precursor of a normal erythrocyte.
Nomenclature
Nomenclature
The term normoblast is sometimes used as a synonym for erythroblast, but at other times it is considered a subcategory. In the latter context, there are two types of erythroblasts:
- “normoblasts” – develop as expected
- “megaloblasts” – an unusually large erythroblast that can be associated with pernicious anemia and folic acid deficiency (collectively called megaloblastic anemia)
Development
Development
There are four stages in the development of a normoblast.
| Image | Description |
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Pronormoblast |
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Basophilic normoblast |
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Polychromatic normoblast (also polychromatophilic) |
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Orthochromatic normoblast (also orthochromatophilic) |
Additional images
Additional images
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Blood cell lineage
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Hematopoiesis
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Blood: Schistocytes: Micro blood film shows an excellent example with normoblast.
External links
External links
- Pronormoblasts Presented by the University of Virginia
- Basophilic Normoblasts Presented by the University of Virginia
- Polychromatophilic Normoblasts Presented by the University of Virginia
- Orthochromatic Normoblasts Presented by the University of Virginia
- Template:Dorlands – “normoblast”
- Template:Dorlands – “erythroblast”
- Template:EMedicineDictionary
- Normoblasts at the US National Library of Medicine Medical Subject Headings (MeSH)
- Histology image: 01804loa – Histology Learning System at Boston University – “Bone Marrow and Hemopoiesis bone marrow smear, erythroblast series with proerythroblast “
- Histology at uiowa.edu
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