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Escherichia coli enteritis classification
Introduction
Overview
Overview
E. coli enteritis may be classified according to the E. coli species into Enterotoxigenic E. coli (ETEC), Enteropathogenic E. coli (EPEC), Enterohemorrhagic E. coli (EHEC), Enteroinvasive E. coli (EIEC), and Enteroaggressive E. coli (EAEC).
Classification
Classification
E. coli enteritis may be classified according to the involved E. coli species listed as follows:
- Enterotoxigenic E. coli (ETEC)
- Enteropathogenic E. coli (EPEC) (including diffusely adherent E. coli [DAEC], a subtype of EPEC)
- Enterohemorrhagic E. coli (EHEC) (may be Shiga-like toxin producing or Verotoxin-producing)
- Enteroinvasive E. coli (EIEC)
- Enteroaggressive E. coli (EAEC)
The following table demonstrates the distinguishing clinical features and pathophysiological mechanisms of various enteritis-causing E. coli strains:
| Properties/Symptoms | ETEC | EPEC | EHEC (STEC or VTEC) |
EIEC |
| Toxin | LT/STa | – | Shiga or Vero toxin | – |
| Invasive | – | – | – | + |
| Intimin | – | + | + | – |
| Enterohemolysin | – | – | + | – |
| Stool | Watery | Watery, Bloody | Watery, very bloody | Mucoid, bloody |
| Fever | Low | + | – | + |
| Fecal leukocytes | – | – | – | + |
| Intestine involved | Small | Small | Colon | Colon, lower small |
| Serology | Various | O26, O111 & others | O157:H7, O26, O111 & others | Various |
| IDb | High | High | Low | High |
a=LT, labile toxin; ST, stable toxin; b=ID, infective dose.
Adapted from Food and Drug Administration (FDA) – Bacteriological Analytical Manual Chapter 4A – Diarrheagenic Escherichia coli.[1]
References
References
- ↑ Feng, Peter; Weagant, Stephen D.; Jinneman, Karen (February 2011). “Bacteriological Analytical Manual Chapter 4A – Diarrheagenic Escherichia coli”. www.fda.gov. Food and Drug Administration. Retrieved December 19 2015. Check date values in:
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Serge Korjian M.D., Yazan Daaboul, M.D.