Esophageal stricture epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahda Alihashemi M.D. [2]

Overview

Most of the esophageal strictures are related to gastroesophageal reflux disease. The overall incidence of esophageal stricture is approximately 11 per 100,000 individuals and the prevalence of esophageal stricture is approximately 70-120 per 100,000 individuals in united states. The incidence of esophageal stricture increases with age. There is no racial predilection to esophageal stricture. The risk of esophageal stricture is higher in men under 60 years but there is similar incidence in men and women after age 60.

Epidemiology and Demographics

Incidence

In one study the overall incidence of esophageal stricture is approximately 11 per 100,000 individuals. The incidence of benign esophageal stricture was 8 per 100,000 individuals and malignant stricture was 3 per 100,000 individuals.^[1]
60–70% of benign strictures of the esophagus are related to gastroesophageal reflux disease.^[2]
Incidence of benign esophageal stricture decreased in recent years because of using proton pump inhibitor (PPI) for treatment of gastroesophageal reflux disease.

Prevalence

The prevalence of esophageal stricture is approximately 70-120 per 100,000 individuals in united states. ^[3]
In Hong kong, the prevalence of benign esophageal stricture was estimated to be 80 cases per 100,000 individuals.^[4]

Case-fatality rate/Mortality rate

Mortality rate of esophageal stricture due to benign causes is not increased compare to normal population, but malignant causes and complications after procedures such as dilation of esophageal stricture can increase mortality.^[1]

Age

The incidence of esophageal stricture increases with age in both of benign and malignant strictures.^[1]

Race

There is no racial predilection to esophageal stricture. Frequency of esophageal stricture was similar in African Americans and non-Hispanic whites.^[5]

Gender

The risk of esophageal stricture due to gastroesophageal reflux disease is higher in men in age group under 60 yr but similar incidence of esophageal stricture in men and women beyond age 60. ^[1]

References

↑ ^1.0 ^1.1 ^1.2 ^1.3 Ruigómez, Ana; Alberto García Rodríguez, Luis; Wallander, Mari-Ann; Johansson, Saga; Eklund, Stefan (2006). “Esophageal Stricture: Incidence, Treatment Patterns, and Recurrence Rate”. The American Journal of Gastroenterology. 101 (12): 2685–2692. doi:10.1111/j.1572-0241.2006.00828.x. ISSN 0002-9270.
↑ Spechler SJ (1999). “AGA technical review on treatment of patients with dysphagia caused by benign disorders of the distal esophagus”. Gastroenterology. 117 (1): 233–54. PMID 10381933.
↑ Fennerty MB (2003). “The continuum of GERD complications”. Cleve Clin J Med. 70 Suppl 5: S33–50. PMID 14705380.
↑ Wong WM, Lam SK, Hui WM, Lai KC, Chan CK, Hu WH, Xia HH, Hui CK, Yuen MF, Chan AO, Wong BC (2002). “Long-term prospective follow-up of endoscopic oesophagitis in southern Chinese–prevalence and spectrum of the disease”. Aliment. Pharmacol. Ther. 16 (12): 2037–42. PMID 12452935.
↑ Vega KJ, Chisholm S, Jamal MM (2009). “Comparison of reflux esophagitis and its complications between African Americans and non-Hispanic whites”. World J. Gastroenterol. 15 (23): 2878–81. PMC 2699005. PMID 19533809.

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[RuigómezAlberto_García_Rodríguez20062-1] 1.0 ^1.1 ^1.2 ^1.3 Ruigómez, Ana; Alberto García Rodríguez, Luis; Wallander, Mari-Ann; Johansson, Saga; Eklund, Stefan (2006). “Esophageal Stricture: Incidence, Treatment Patterns, and Recurrence Rate”. The American Journal of Gastroenterology. 101 (12): 2685–2692. doi:10.1111/j.1572-0241.2006.00828.x. ISSN 0002-9270.

[pmid10381933-2] Spechler SJ (1999). “AGA technical review on treatment of patients with dysphagia caused by benign disorders of the distal esophagus”. Gastroenterology. 117 (1): 233–54. PMID 10381933.

[pmid14705380-3] Fennerty MB (2003). “The continuum of GERD complications”. Cleve Clin J Med. 70 Suppl 5: S33–50. PMID 14705380.

[pmid12452935-4] Wong WM, Lam SK, Hui WM, Lai KC, Chan CK, Hu WH, Xia HH, Hui CK, Yuen MF, Chan AO, Wong BC (2002). “Long-term prospective follow-up of endoscopic oesophagitis in southern Chinese–prevalence and spectrum of the disease”. Aliment. Pharmacol. Ther. 16 (12): 2037–42. PMID 12452935.

[pmid19533809-5] Vega KJ, Chisholm S, Jamal MM (2009). “Comparison of reflux esophagitis and its complications between African Americans and non-Hispanic whites”. World J. Gastroenterol. 15 (23): 2878–81. PMC 2699005. PMID 19533809.

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