Essential thrombocytosis epidemiology and demographics

The incidence of essential thrombocytosis is approximately 0.6-2.5 cases per 100,000 individuals worldwide annually.^[1] The prevalence of essential thrombocytosis is about 30 for every 100,000 people worldwide.^[2] The incidence of essential thrombocytosis increases with age; the median age at diagnosis is 65-70 years. Patients of all age groups may develop essential thrombocytosis. However it commonly affects individuals older than 60 years of age.^[3] Females are more commonly affected with essential thrombocytosis than males.^[3] The female to male ratio is approximately 2 to 1.^[1]

• The annual incidence of essential thrombocytosis is estimated to be 0.6-2.5 cases per 100,000 individuals worldwide.^[1]
• The annual incidence rate of ET in the US is 1.5 per 100,000 persons (age-standardized incidence 1.6 per 100,000 in a Swedish population-based study). The median age at diagnosis is 59 years.^[4]
• In reality, the incidence may be much more higher attributing the incidental diagnosis of the condition where many go undiagnosed due to lack of routine medical care.

• Worldwide, the prevalence of essential thrombocytosis is approximately 30 for every 100,000 individuals worldwide.^[2].

• Patients of all age groups may develop essential thrombocytosis. However it commonly affects individuals older than 60 years of age.^[3]
• The median age at onset is 65-70 years.

• Women in their third decade of life are more commonly affected with essential thrombocytosis than men at same age. The female to male ratio is approximately 2:1.^[5]
• Patients who present in the 6th decade of life usually have same incidence in both men and women.

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