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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Essential thrombocytosis other diagnostic studies

Introduction

Overview

Overview

Bone marrow biopsy is an important test and needed to make a diagnosis of essential thrombocytosis.[1] On bone marrow biopsy, essential thrombocytosis is characterized by bone marrow hypercellularity with clusters of megakaryocytes that stain positive for iron, increased reticulin, and no collagen fibrosis.

Bone marrow biopsy findings

Bone marrow biopsy findings

  • Bone marrow biopsy is an important test and needed to make a diagnosis of essential thrombocytosis.[1]
  • On bone marrow biopsy, essential thrombocytosis is characterized by:
    • Increased cellularity
    • Hyperplasia and clustering of megakaryocytes
    • Bone marrow stains positive for iron
    • Bone marrow reticulin may be increased with no collagen fibrosis
References

References

  1. ↑ 1.0 1.1 Sanchez S, Ewton A (2006). “Essential thrombocythemia: a review of diagnostic and pathologic features”. Arch Pathol Lab Med. 130 (8): 1144–50. doi:10.1043/1543-2165(2006)130[1144:ET]2.0.CO;2. PMID 16879015.


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]