Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Essential thrombocytosis screening
Introduction
Overview
Overview
Screening for essential thrombocytosis by cell-based quantitative assays for JAK2V617F mutation is recommended among individuals with a positive family history for the disease (autosomal dominant inheritance) and in patients who present with thrombocytosis, erythrocytosis, and monocytosis.[1][2]
Screening
Screening
Screening for essential thrombocytosis by cell-based quantitative assays for JAK2V617F mutation is recommended among the following:[1][2]
- Individuals with a family history of essential thrombocytosis (autosomal dominant inheritance)
- Patients who present with thrombocytosis, erythrocytosis, and monocytosis.
References
References
- ↑ 1.0 1.1 The Asco Post. JAK2 and MPL Mutation Screening: What Are the Indications and How to Interpret the Results. http://www.ascopost.com/issues/february-15-2012/jak2-and-mpl-mutation-screening-what-are-the-indications-and-how-to-interpret-the-results.aspx
- ↑ 2.0 2.1 Tefferi A, Noel P, Hanson CA (2011). “Uses and abuses of JAK2 and MPL mutation tests in myeloproliferative neoplasms a paper from the 2010 William Beaumont hospital symposium on molecular pathology”. J Mol Diagn. 13 (5): 461–6. doi:10.1016/j.jmoldx.2011.05.007. PMC 3157620. PMID 21723416.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]