Euthyroid sick syndrome medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Akshun Kalia M.B.B.S.[2]

Overview

In euthyroid sick syndrome emphasis is on rapid correction of underlying disease. Many seriously ill patients have low levels of thyroid hormones but are not clinically hypothyroid and do not require thyroid hormone supplementation. Replacement of thyroid hormones in euthyroid sick syndrome is controversial except, in patients of congestive heart failure where liothyronine (LT3) or levothyroxine (LT4) may be recommended, to improve ventricular performance. Therefore, thyroid hormone therapy is generally not recommended for patients with euthyroid sick syndrome, except possibly those with chronic heart failure.

Medical Therapy

In euthyroid sick syndrome emphasis is on rapid correction of underlying disease. Many seriously ill patients have low levels of thyroid hormones but are not clinically hypothyroid and do not require thyroid hormone supplementation. Replacement of thyroid hormones in euthyroid sick syndrome is controversial except, in patients of congestive heart failure where liothyronine (LT3) or levothyroxine (LT4) may be recommended, to improve ventricular performance. Therefore, thyroid hormone therapy is generally not recommended for patients with euthyroid sick syndrome, except possibly those with chronic heart failure.^[1]^[2]^[3]

References

↑ Template:Citejournal
↑ Becker RA, Vaughan GM, Ziegler MG, Seraile LG, Goldfarb IW, Mansour EH, McManus WF, Pruitt BA, Mason AD (1982). “Hypermetabolic low triiodothyronine syndrome of burn injury”. Crit. Care Med. 10 (12): 870–5. PMID 7140337.
↑ Zarechnaia SN, Panfilova IM, Zhezherukha LI, Moroz EM, Perekopskaia TN (1989). “[Multiyear ecologic faunistic research on Culicidae in Dnepropetrovsk Province. 1]”. Med Parazitol (Mosk) (in Russian) (6): 44–9. PMID 2576461.

Overview