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Extraglomerular mesangial cell
Introduction
Overview
Overview
Extraglomerular mesangial cells (or lacis cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.
Lacis cells form the juxtaglomerular apparatus in combination with two other types of cells: the macula densa of the thick ascending limb of Henle and Juxtaglomerular cells of the afferent arteriole. This apparatus controls blood pressure through the Renin-Angiotensin-Aldosterone system. The specific function of Lacis cells is not well understood. Although is it has been associated with the secretion of EPO. [1]