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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Extramammary Paget's disease epidemiology and demographics

Introduction

Overview

Overview

Extramammary Paget’s disease is rare, and its exact incidence is unknown. Extramammary Paget’s disease commonly affects individuals 50-60 years of age. Females are more commonly affected with the disease than males. The female to male ratio is approximately 3-4.5 to 1. It usually affects individuals of the Caucasian race, but it may occur in other races.

Epidemiology and Demographics

Epidemiology and Demographics

Incidence

  • Extramammary Paget’s disease is rare, and the exact incidence is unknown.
  • The incidence of extramammary Paget’s disease is estimated to be 0.10 per 100,000 individuals.
  • However, in older reports, it represented 6.5% of all cases of all Paget diseases.

Age

  • The peak age incidence of vulvar extramammary Paget’s disease is approximately 50-65 years.[1][2]
  • The median age for a diagnosis of scrotal and penile disease is approximately 70-75 years.

Gender

Females are more commonly affected with extramammary Paget’s disease than males. The female to male ratio is approximately 3-4.5 to 1.[3]

Race

Extramammary Paget’s disease usually affects individuals of the Caucasian race, but it may occur in other races.[4]

References

References

  1. ↑ Curtin JP, Rubin SC, Jones WB, Hoskins WJ, Lewis JL (1990). “Paget’s disease of the vulva”. Gynecol Oncol. 39 (3): 374–7. PMID 2175288.
  2. ↑ Lloyd J, Flanagan AM (2000). “Mammary and extramammary Paget’s disease”. J Clin Pathol. 53 (10): 742–9. PMC 1731095. PMID 11064666.
  3. ↑ Chanda JJ (1985). “Extramammary Paget’s disease: prognosis and relationship to internal malignancy”. J Am Acad Dermatol. 13 (6): 1009–14. PMID 3001158.
  4. ↑ Zollo, J.D.; Zeitouni, N.C. (2000). “The Roswell Park Cancer Institute experience with extramammary Paget’s disease”. British Journal of Dermatology. 142 (1): 59–65. doi:10.1046/j.1365-2133.2000.03242.x. ISSN 0007-0963.


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]