Extranodal NK-T-cell lymphoma causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD [2]

Overview

Extranodal NK/T-cell lymphoma is caused by transition mutation of p53. P53 overexpresion has assosiation with poor prognosis.

Causes

Common causes of extranodal NK-T cell lymphoma may include:^[1]

Extranodal NK/T-cell lymphoma is caused by transition mutation of p53.^[2]
Genetic instability of micro satellites was not found in cases with the disease.^[3]
P53 overexertion has association with poor prognosis.

Cardiovascular	No underlying causes
Chemical/Poisoning	No underlying causes
Dental	No underlying causes
Dermatologic	No underlying causes
Drug Side Effect	No underlying causes
Ear Nose Throat	No underlying causes
Endocrine	No underlying causes
Environmental	No underlying causes
Gastroenterologic	No underlying causes
Genetic	No underlying causes
Hematologic	No underlying causes
Iatrogenic	No underlying causes
Infectious Disease	EBV infection
Musculoskeletal/Orthopedic	No underlying causes
Neurologic	No underlying causes
Nutritional/Metabolic	No underlying causes
Obstetric/Gynecologic	No underlying causes
Oncologic	P53 mutation
Ophthalmologic	No underlying causes
Overdose/Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal/Electrolyte	No underlying causes
Rheumatology/Immunology/Allergy	No underlying causes
Sexual	No underlying causes
Trauma	No underlying causes
Urologic	No underlying causes
Miscellaneous	No underlying causes

List the causes of the disease in alphabetical order:

References

↑ Harabuchi, Yasuaki; Takahara, Miki; Kishibe, Kan; Nagato, Toshihiro; Kumai, Takumi (2019). “Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type: Basic Science and Clinical Progress”. Frontiers in Pediatrics. 7. doi:10.3389/fped.2019.00141. ISSN 2296-2360.
↑ Aozasa, Katsuyuki; Takakuwa, Tetsuya; Hongyo, Tadashi; Yang, Woo-Ick (2008). “Nasal NK/T-cell lymphoma: epidemiology and pathogenesis”. International Journal of Hematology. 87 (2): 110–117. doi:10.1007/s12185-008-0021-7. ISSN 0925-5710.
↑ Greenblatt MS, Bennett WP, Hollstein M, Harris CC (1994). “Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis”. Cancer Res. 54 (18): 4855–78. PMID 8069852.

Overview