Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
FAAH2
Introduction
Fatty acid amide hydrolase 2 or FAAH2 (EC 3.5.1.99, oleamide hydrolase 2, anandamide amidohydrolase 2) is a member of the serine hydrolase family of enzymes.[1]
Fatty acid amide hydrolase 2 degrades endocannabinoids and defects in this enzyme have been associated with neurologic and psychiatric disorders.[2]
References
References
- ↑ Wei BQ, Mikkelsen TS, McKinney MK, Lander ES, Cravatt BF (December 2006). “A second fatty acid amide hydrolase with variable distribution among placental mammals”. The Journal of Biological Chemistry. 281 (48): 36569–78. doi:10.1074/jbc.M606646200. PMID 17015445.
- ↑ Sirrs S, van Karnebeek CD, Peng X, Shyr C, Tarailo-Graovac M, Mandal R, et al. (March 2015). “Defects in fatty acid amide hydrolase 2 in a male with neurologic and psychiatric symptoms”. Orphanet Journal of Rare Diseases. 10: 38. doi:10.1186/s13023-015-0248-3. PMC 4423390. PMID 25885783.