Health Dictionary
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FAM47E-STBD1
Introduction
FAM47E-STBD1 readthrough is a protein that in humans is encoded by the FAM47E-STBD1 gene.[1]
Function
Function
This locus represents naturally occurring read-through transcription between the neighboring FAM47E (family with sequence similarity 47, member E) and STBD1 (starch binding domain 1) genes on chromosome 4. The read-through transcript encodes a protein that shares sequence identity with the upstream gene product but its C-terminal region is distinct due to frameshifts relative to the downstream gene.[1]
Further reading
Further reading
- Simón-Sánchez J, Schulte C, Bras JM, Sharma M, Gibbs JR, Berg D, et al. (December 2009). “Genome-wide association study reveals genetic risk underlying Parkinson’s disease”. Nature Genetics. 41 (12): 1308–12. doi:10.1038/ng.487. PMC 2787725. PMID 19915575.
- Do CB, Tung JY, Dorfman E, Kiefer AK, Drabant EM, Francke U, Mountain JL, Goldman SM, Tanner CM, Langston JW, Wojcicki A, Eriksson N (June 2011). “Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson’s disease”. PLoS Genetics. 7 (6): e1002141. doi:10.1371/journal.pgen.1002141. PMCÂ 3121750. PMIDÂ 21738487.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.