
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions β written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
FCRL4
Introduction
Fc receptor-like protein 4 is a protein that in humans is encoded by the FCRL4 gene. FCRL4 is an inhibitory receptor expressed on human memory B cells which resides in epithelial tissues.[1][2][3]
References
References
- β Hatzivassiliou G, Miller I, Takizawa J, Palanisamy N, Rao PH, Iida S, Tagawa S, Taniwaki M, Russo J, Neri A, Cattoretti G, Clynes R, Mendelsohn C, Chaganti RS, Dalla-Favera R (Apr 2001). “IRTA1 and IRTA2, novel immunoglobulin superfamily receptors expressed in B cells and involved in chromosome 1q21 abnormalities in B cell malignancy”. Immunity. 14 (3): 277β89. doi:10.1016/S1074-7613(01)00109-1. PMIDΒ 11290337.
- β Davis RS, Wang YH, Kubagawa H, Cooper MD (Aug 2001). “Identification of a family of Fc receptor homologs with preferential B cell expression”. Proc Natl Acad Sci U S A. 98 (17): 9772β7. doi:10.1073/pnas.171308498. PMCΒ 55528. PMIDΒ 11493702.
- β “Entrez Gene: FCRL4 Fc receptor-like 4”.
Further reading
Further reading
- Taylor AI, Gould HJ, Sutton BJ, Calvert RA (2007). “The first avian Ig-like Fc receptor family member combines features of mammalian FcR and FCRL”. Immunogenetics. 59 (4): 323β8. doi:10.1007/s00251-007-0195-9. PMIDΒ 17273841.
- Ehrhardt GR, Hsu JT, Gartland L, et al. (2005). “Expression of the immunoregulatory molecule FcRH4 defines a distinctive tissue-based population of memory B cells”. J. Exp. Med. 202 (6): 783β91. doi:10.1084/jem.20050879. PMCΒ 2212938. PMIDΒ 16157685.
- JΓΆhrens K, Shimizu Y, Anagnostopoulos I, et al. (2006). “T-bet-positive and IRTA1-positive monocytoid B cells differ from marginal zone B cells and epithelial-associated B cells in their antigen profile and topographical distribution”. Haematologica. 90 (8): 1070β7. PMIDΒ 16079106.
- Falini B, Tiacci E, Pucciarini A, et al. (2004). “Expression of the IRTA1 receptor identifies intraepithelial and subepithelial marginal zone B cells of the mucosa-associated lymphoid tissue (MALT)”. Blood. 102 (10): 3684β92. doi:10.1182/blood-2003-03-0750. PMIDΒ 12881317.
- Guselnikov SV, Ershova SA, Mechetina LV, et al. (2002). “A family of highly diverse human and mouse genes structurally links leukocyte FcR, gp42 and PECAM-1”. Immunogenetics. 54 (2): 87β95. doi:10.1007/s00251-002-0436-x. PMIDΒ 12037601.
- Miller I, Hatzivassiliou G, Cattoretti G, et al. (2002). “IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells”. Blood. 99 (8): 2662β9. doi:10.1182/blood.V99.8.2662. PMIDΒ 11929751.
