Colonoscopy is considered as a gold standard for evaluating intestine, diagnostic and therapeutic approaches. Tissue biopsy and polypectomy could be done during colonoscopy. Findings on a colonoscopy and flexible sigmoidoscopy suggestive of familial adenomatous polyposis include visual detection of multiple colon polyps. Colonoscopy has 0.02% mortality and 0.2% morbidity 0.2%. Colonoscopy has side effects including pain, risk of perforation and bleeding.

• Colonoscopy may be helpful in the diagnosis of familial adenomatous polyposis.^{[1][2][3][4][5]}
  • Colonoscopy is considered as a gold standard for evaluating intestine, diagnostic and therapeutic approaches.
  • Findings on a colonoscopy suggestive of familial adenomatous polyposis include visual detection of multiple colon polyps.
  • Tissue biopsy and polypectomy could be done during colonoscopy.
  • Colonoscopy has side effects including:
    • Mortality 0.02%
    • Morbidity 0.2%
    • Pain
    • Perforation 0.03-0.06%
    • Bleeding

• Flexible sigmoidoscopy may be helpful in the diagnosis of familial adenomatous polyposis.^[1][7]
  • Findings on a flexible sigmoidoscopy suggestive of familial adenomatous polyposis include visual detection of multiple colon polyps.
  • Flexible sigmoidoscopy may be performed for re-examination and follow-up.

• Capsule endoscopy may be helpful in the diagnosis of familial adenomatous polyposis.^[9]
  • Findings on a capsule endoscopy suggestive of colon polyps include visual detection of multiple polyps.
  • It assesses the location, size, and number of small-bowel polyps.
  • It is recommended for the surveillance of jejunal-ileal polyps in selected patients.
  • Relative contraindication for capsule endoscopy is abdominal surgery.
• Forward-viewing and side-viewing endoscopy may be helpful in the diagnosis of familial adenomatous polyposis.
  • Forward-viewing and side-viewing endoscopy are used for surveillance of periampullary and duodenal polyposis.

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