Fanconi anemia risk factors

The major risk factor for Fanconi anemia is genetic inheritance. It is inherited in an autosomal recessive pattern.

The major risk factor for Fanconi anemia is genetic inheritance. It is inherited in an autosomal recessive pattern, meaning that both parents must harbor the gene mutation to have an affected child. There are no other particular risk factors for Fanconi anemia. This is a genetic disorder that is caused by a mutation in genes involved in DNA damage response. Patients with Fanconi anemia are more susceptible to malignancy such as acute myeloid leukemia, and a risk factor for development of malignancies includes exposure to radiation and carcinogens.^[1]

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