Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Fatty liver natural history, complications and prognosis
Introduction
Natural History
Natural History
Complications
Complications
Up to 10% of cirrhotic alcoholic FLD will develop hepatocellular carcinoma. Overall incidence of liver cancer in non-alcoholic FLD has not been assessed yet but the association is well established.[1]
A retrospective cohort study concluded that liver failure is the main cause of morbidity and mortality in NASH-associated cirrhosis. The prognosis is either similar or less severe than HCV-cirrhosis.[2]
Prognosis
Prognosis
Prognosis can be determined by:
- FIB-4
- Liver stiffness measurement
- Vibration-controlled elastography (VCTE), Fibroscan
- Magnetic resonance elastography (MRE)
References
References
- ↑ Qian Y, Fan JG (2005). “Obesity, fatty liver and liver cancer”. HBPD INT. 4 (2): 173–7. PMID 15908310.
- ↑ Hui JM, Kench JG, Chitturi S; et al. (2003). “Long-term outcomes of cirrhosis in nonalcoholic steatohepatitis compared with hepatitis C”. Hepatology. 38 (2): 420–7. doi:10.1053/jhep.2003.50320. PMID 12883486.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]