Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Fever of unknown origin natural history, complications and prognosis
Introduction
Synonyms and keywords: febris continua e causa ignota; febris e causa ignota; febris E.C.I.; FUO; PUO; pyrexia of unknown origin
Overview
Overview
fever of unknown origin has different etiologies it is therefore important to mention that course, complication and prognosis of disease depends on the underlying etiology. In case of old aged patients or patients with malignancy prognosis is poor.
Natural History, Complications and Prognosis
Natural History, Complications and Prognosis
- The course and prognosis of disease dependent on the underlying cause of FUO.[1][2]
- If the cause is found earlier and treatment is directed towards it prognosis is usually good
- In patients with neutropenic and HIV related FUO the disease can cause many complication due to their immunocompromised state
- Prognosis is poor in case of old age patients or when malignancy is the cause of FUO
- In more than 50Â % cases cause is unknown despite extensive investigation in such cases prognosis is good.
References
References
- ↑ Wright WF, Auwaerter PG (2020). “Fever and Fever of Unknown Origin: Review, Recent Advances, and Lingering Dogma”. Open Forum Infect Dis. 7 (5): ofaa132. doi:10.1093/ofid/ofaa132. PMC 7237822 Check
|pmc=value (help). PMID 32462043 Check|pmid=value (help). - ↑ Mulders-Manders C, Simon A, Bleeker-Rovers C (2015). “Fever of unknown origin”. Clin Med (Lond). 15 (3): 280–4. doi:10.7861/clinmedicine.15-3-280. PMC 4953114. PMID 26031980.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]