Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Fibrin Degradation Products
Introduction
Synonyms and Keywords: FDP
Overview
Overview
Fibrin degradation products are formed during the metabolism of fibrinogen and fibrin via plasmin. Fibrin degradation product (FDPs) are components of the blood produced by clot degeneration.[1]
| Reference Range | |
| Fribin Degradation Products | < 1 mg/l |
| D-Dimers | 20-400 ug/l |
Differential Diagnosis
Differential Diagnosis
In alphabetical order. [2] [3]
Increased
- Bladder carcinoma
- Contact with body-foreign surfaces
- Disseminated Intravascular Coagulation (DIC)
- Drugs
- False positive, if Rheumatoid factor is present
- Fibrinolytic therapy
- Postoperative
- Pulmonary Embolism
- Release of plasmin from plasminogen-rich organs (lungs, pancreas, prostate)
- Severe Liver Disease
- Subdural hematomas
- Thromboses
- Tumor
- Venous and arterial thrombotic events
References
References
- ↑ Gaffney PJ, Edgell T, Creighton-Kempsford LJ, Wheeler S, Tarelli E (1995). “Fibrin degradation product (FnDP) assays: analysis of standardization issues and target antigens in plasma”. Br. J. Haematol. 90 (1): 187–94. PMID 7786784.
- ↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
- ↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]