Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Fifth disease historical perspective
Introduction
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Overview
Overview
Fifth disease is also referred to as erythema infectiosum (meaning infectious redness) and as Human Parvovirus B19 Infection, Slapped cheek syndrome, Slapcheek, Slap face or Slapped face. It is a mild rash illness that occurs most commonly in children. The name “fifth disease” derives from its historical classification as the fifth of the classical childhood skin rashes or exanthems. In 1975, the cause of Fifth disease was discovered to be parvovirus B19.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]