Fifth disease historical perspective

Fifth disease is also referred to as erythema infectiosum (meaning infectious redness) and as Human Parvovirus B19 Infection, Slapped cheek syndrome, Slapcheek, Slap face or Slapped face. It is a mild rash illness that occurs most commonly in children. The name “fifth disease” derives from its historical classification as the fifth of the classical childhood skin rashes or exanthems. In 1975, the cause of Fifth disease was discovered to be parvovirus B19.

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