As a normal body function, the action of flatulence is an important signal of normal bowel activity and hence is often documented by nursing staff following surgical or other treatment of patients. However, symptoms of excessive flatulence can indicate the presence of irritable bowel syndrome or some other organic disease. In particular, the sudden occurrence of excessive flatulence together with the onset of new symptoms provide reason for seeking further medical examination. Flatulence is not poisonous; it is a natural component of various intestinal contents. However, discomfort may develop from the build-up of gas pressure. In theory, pathological distension of the bowel, leading to constipation, could result if a person holds in flatus. Not all flatus is released from the body via the anus. When the partial pressure of any gas component of the intestinal lumen is higher than its partial pressure in the blood, that component enters into the bloodstream of the intestinal wall by the process of diffusion. As the blood passes through thelungs this gas can diffuse back out of the blood and be exhaled. If a person holds in flatus during daytime, it will often be released during sleep when the body is relaxed. Some flatus can become trapped within the feces during its compaction and will exit the body, still contained within the fecal matter, during the process ofdefecation.