Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Focal segmental glomerulosclerosis epidemiology and demographics
Introduction
Overview
Overview
Epidemiology and Demographics
Epidemiology and Demographics
Incidence
Incidence
- The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
- In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
Prevalence
- The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
- In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
- The prevalence of [disease/malignancy] is estimated to be [number] cases annually.
Case-fatality rate/Mortality rate
- In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
- The case-fatality rate/mortality rate of [disease name] is approximately [number range].
Age
Age
FSGS is considered a disease of the adult population (compared to minimal change disease which is more common among children). The median age of non-HIV associated FSGS leading to ESRD is 40-49 years in black adults and 70-79 in white and Asian adults.[1]
Gender
Gender
- Men are more commonly affected by focal segmental glomerulosclerosis than women
- The prevalence of FSGS male to female ratio is 1.5-2 to 1[1]
Race
FSGS is the most common primary renal cause of end-stage renal disease (ESRD) in whites and blacks, contributing to approximately 2% of ESRD.[1] FSGS is more common in blacks. It accounts for approximately 35% of nephrotic syndromes in all cases and approximately 50% of nephrotic syndrome in blacks.[2] FSGS seems to have a higher incidence in Blacks with a familial pattern of inheritance especially in Blacks with family history of ESKD.[3]
References
References
- ↑ 1.0 1.1 1.2 Kitiyakara C, Eggers P, Kopp JB (2004). “Twenty-one-year trend in ESRD due to focal segmental glomerulosclerosis in the United States”. Am J Kidney Dis. 44 (5): 815–25. PMID 15492947.
- ↑ Hogg R, Middleton J, Vehaskari VM (2007). “Focal segmental glomerulosclerosis–epidemiology aspects in children and adults”. Pediatr Nephrol. 22 (2): 183–6. doi:10.1007/s00467-006-0370-5. PMC 1764601. PMID 17151873.
- ↑ Reiser J, Nast CC, Alachkar N (2014). “Permeability factors in focal and segmental glomerulosclerosis”. Adv Chronic Kidney Dis. 21 (5): 417–21. doi:10.1053/j.ackd.2014.05.010. PMC 4149759. PMID 25168830 PMID 25168830 Check
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]