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Focal segmental glomerulosclerosis physical examination

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]

Overview

Overview

Patients with [disease name] usually appear [general appearance]. Physical examination of patients with [disease name] is usually remarkable for [finding 1], [finding 2], and [finding 3].

OR

Common physical examination findings of [disease name] include [finding 1], [finding 2], and [finding 3].

OR

The presence of [finding(s)] on physical examination is diagnostic of [disease name].

OR

The presence of [finding(s)] on physical examination is highly suggestive of [disease name].

Physical Examination

Physical Examination

Physical examination of patients with focal segmental glomerulosclerosis is usually normal except there are signs of fluid overload if the disease progress to end-stage renal failure.[1]

Appearance of the Patient

  • Patients with focal segmental glomerulosclerosis usually appear lethargic

Vital Signs

  • Afebrile
  • High blood pressure with normal pulse pressure

Skin

  • Skin examination of patients with focal segmental glomerulosclerosis is usually normal

HEENT

  • HEENT examination of patients with focal segmental glomerulosclerosis is usually normal
  • Swelling of periorbital sometimes resulting in swollen-shut eyelids

Neck

  • Neck examination of patients with focal segmental glomerulosclerosis is usually normal
  • Jugular venous distension is seen in fluid overload

Lungs

  • Pulmonary examination of patients with focal segmental glomerulosclerosis is usually normal, however, if there is fluid overload, following signs are seen:
  • Lungs are hyporesonant
  • Fine/coarse crackles upon auscultation of the lung bases bilaterally

Heart

  • Cardiovascular examination of patients with focal segmental glomerulosclerosis is usually normal

Abdomen

Back

  • Back examination of patients with focal segmental glomerulosclerosis is usually normal

Genitourinary

  • Signs of fluid overload can be seen which includes:
    • Scrotal edema
    • Vulvar edema

Neuromuscular

  • Neuromuscular examination of patients with focal segmental glomerulosclerosis is usually normal

Extremities

  • Pitting/non-pitting edema of the upper and lower extremitiesdue to fluid overload
References

References

  1. D’Agati VD, Kaskel FJ, Falk RJ (December 2011). “Focal segmental glomerulosclerosis”. N. Engl. J. Med. 365 (25): 2398–411. doi:10.1056/NEJMra1106556. PMID 22187987.

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