
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Frailty syndrome
Introduction
The frailty syndrome is a collection of symptoms or markers that place (mostly) older adults at increased risk of adverse events such as death, disability, and institutionalization. The term “frailty” has been used quite often in the gertontological literature without a firm definition of the state. Recently though Linda Fried (2001) and associates operationalized and validated a measure of frailty in the Cardiovascular Health Study and then later in the Women’s Health and Aging Study. Frailty is determined based on cutoffs in 5 components – Muscle weakness, weight loss, low physical activity, exhaustion, and slow walking speed. Subjects below certain cutoffs on 3 or more components are deemed frail, those with 1-2 components below cutoffs are deemed intermediately or moderately frail, and those scoring higher than cut points on all 5 measures are deemed non-frail or robust.
