Health Dictionary
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GAS7 gene
Introduction
Growth arrest-specific protein 7 is a protein that in humans is encoded by the GAS7 gene.[1][2]
Growth arrest-specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 plays a putative role in neuronal development. Several transcript variants encoding proteins which vary in the N-terminus have been described.[2]
References
References
- ↑ Ju YT, Chang AC, She BR, Tsaur ML, Hwang HM, Chao CC, Cohen SN, Lin-Chao S (Oct 1998). “gas7: A gene expressed preferentially in growth-arrested fibroblasts and terminally differentiated Purkinje neurons affects neurite formation”. Proc Natl Acad Sci U S A. 95 (19): 11423–11428. doi:10.1073/pnas.95.19.11423. PMC 21658. PMID 9736752.
- ↑ 2.0 2.1 “Entrez Gene: GAS7 growth arrest-specific 7”.
Further reading
Further reading
- Kurtz A, Zimmer A (1995). “Interspecies fluorescence in situ hybridization further defines synteny homology between mouse chromosome 11 and human chromosome 17”. Mamm. Genome. 6 (5): 379–380. doi:10.1007/BF00364810. PMID 7626897.
- Maruyama K, Sugano S (1994). “Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides”. Gene. 138 (1–2): 171–174. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). “Construction and characterization of a full length-enriched and a 5′-end-enriched cDNA library”. Gene. 200 (1–2): 149–156. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Ishikawa K, Nagase T, Nakajima D, et al. (1998). “Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro”. DNA Res. 4 (5): 307–313. doi:10.1093/dnares/4.5.307. PMID 9455477.
- Megonigal MD, Cheung NK, Rappaport EF, et al. (2000). “Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors”. Proc. Natl. Acad. Sci. U.S.A. 97 (6): 2814–2819. doi:10.1073/pnas.050397097. PMC 16012. PMID 10706619.
- She BR, Liou GG, Lin-Chao S (2002). “Association of the growth-arrest-specific protein Gas7 with F-actin induces reorganization of microfilaments and promotes membrane outgrowth”. Exp. Cell Res. 273 (1): 34–44. doi:10.1006/excr.2001.5435. PMID 11795944.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Chao CC, Chang PY, Lu HH (2005). “Human Gas7 isoforms homologous to mouse transcripts differentially induce neurite outgrowth”. J. Neurosci. Res. 81 (2): 153–162. doi:10.1002/jnr.20552. PMID 15948147.