Gallbladder cancer epidemiology and demographics

Around 80 t0 95% of biliary tract cancers are gallbladder cancers. Epidemiological research has recognized striking geographic and ethnic difference. An excessive incidence in American Indians and Southeast Asia, but pretty low in the America and the arena.

• The countries with high incidence have high mortality rate because mortality rate relatively follows incidence.
• American Indian and Alaska Native people had the highest gallbladder cancer incidence.

• The prevalence of gallbladder cancer is approximately 21 per 100,000 cancer incidence and 75.8% gallstone prevalence in pima indian females.^[1]
• The prevalence of gallbladder cancer is approximately 7.1 per 100,000 and 64.1% in North American Indian females.^[2]
• The prevalence of gallbladder cancer is approximately 27.3 per 100,000 and 49.4% in Chilean Mapuche Indian females.^[3]

• The prevalence of gallbladder cancer is approximately 22 per 100,000 and 21.6% in East Indian females.

• The mortality rate of gallbladder cancer is approximately 0.6%.
• An estimated 1,092 gallstone-related deaths for 2004 in the U.S.^[4]
• cholecystectomy carries a high mortality rate at 1% and postoperative complications of >30%.^[5]
• The mortality rate of gallbladder cancer in chile is very high in the world.^[6]

• The incidence of gallbladder cancer increases with age over 65 years.
• Gallbladder adenocarcinoma most commonly affects older persons with chronic cholecystolithiasis.

• Females are more commonly affected by gallbladder cancer than men.The female to male gender ratio is approximately 3 to 1.^[7]
• Women with more gravidity and parity increase the risk of developing gallbladder cancer.^[8]

• Gallbladder cancer usually affects individuals of  Chile, Bolivia, Ecuador, India, Pakistan, Japan, and Korea more than the rest of the world.^[9]

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