Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Gastric antral vascular ectasia causes
Introduction
Overview
Overview
Causes
Causes
65% of patients with both cirrhosis and GAVE are male, but a total of 30% have both conditions. The causal connection between cirrhosis and GAVE has not been proven.
A connective tissue disease has been suspected in some cases.
Autoimmunity may have something to do with it,[1] as 25% of all sclerosis patients who had a certain anti-RNA marker have GAVE. RNA autoimmunity has been suspected as a cause or marker since at least 1996.
One theory current since the 1990s focuses on a history of prolapse of the stomach into the small intestine.
Gastrin levels may indicate a hormonal connection. This may be due to vasoactive intestinal peptide and 5-hydroxy-tryptamine.
It is also possible that infection by H. pylori can cause it.
References
References
- ↑ Valdez, BC; Henning, D; Busch, RK; Woods, K; Flores-Rozas, H; Hurwitz, J; Perlaky, L; Busch, H (1996). “A nucleolar RNA helicase recognized by autoimmune antibodies from a patient with watermelon stomach disease”. Nucleic Acids Research. 24 (7): 1220–4. doi:10.1093/nar/24.7.1220. PMC 145780. PMID 8614622.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]