Gitoformate
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Overview
Gitoformate (INN, or pentaformylgitoxin, trade name Dynocard) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). Produced by Madaus, it is not available in the US, and does not seem to be available in Europe either.
Chemistry
Chemistry
Gitoformate is a derivative of the glycoside gitoxin, with five of the six free hydroxyl groups formylated, one on the aglycon and four on the sugar.[1][2] Gitoxin, a cardiac glycoside from the Woolly Foxglove (Digitalis lanata), has an aglycon of the cardenolide type named gitoxigenin, which is also the aglycon of lanatoside B, another Digitalis lanata glycoside.[3]
References
References
- ↑ PMID 6542412 (PMID 6542412)
Citation will be completed automatically in a few minutes. Jump the queue or expand by hand - ↑ Template:PubChem
- ↑ William O. Foye,Thomas L. Lemke, David A. Williams. Foye’s principles of medicinal chemistry. p. 699. ISBN 978-0-7817-6879-5.
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