Glioblastoma multiforme causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Marjan Khan M.B.B.S.[2]

Overview

Common causes of glioblastoma multiforme include genetic mutations.^[1]


Type of glioblastoma multiforme	Genes

Primary	Mdm2 PTEN Gene on chromosome 10p
Secondary	IDH1 p53 Gene on chromosome 10q Gene on chromosome 17p Gene on chromosome 19q
Classic	EGFR
Proneural	TP53 PDGFRA IDH1
Mesenchymal	NF-1

Causes

Common causes of glioblastoma multiforme include genetic mutations.^[1]


Type of glioblastoma multiforme	Genes

Primary	Mdm2 PTEN Gene on chromosome 10p
Secondary	IDH1 p53 Gene on chromosome 10q Gene on chromosome 17p Gene on chromosome 19q
Classic	EGFR
Proneural	TP53 PDGFRA IDH1
Mesenchymal	NF-1

References

↑ ^1.0 ^1.1 Etiology of glioblastoma multiforme. Dr Dylan Kurda and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/glioblastoma

Overview